Rickettsia Conorii is an obligate intracellular gram-negative bacterium that causes a spectrum of different syndromes. An 83-year-old splenectomised patient has septic shock associated with coagulopathy and multi-organ-failure. The patient is treated with doxycycline, vasoactive amines, fresh frozen plasma, antithrombin III with progressive clinical improvement. Mediterranean spotted fever is a pathology that frequently has benign characteristics however, in fragile patients it can manifest itself with severe clinical conditions.
Damiano Larnè, Maria Polimeni, Rosa Basile, Mariastella Carpentieri, Saverio De Lorenzo, Giuseppe Ieropoli, Alfredo Kunkar, Santa Pellicano, Domenico Sofo, and Giuseppe Foti